South Africa start as strong favourites for the five one-dayers with a number of the visitors' squad struggling with injury.
MORE
Australia won the Natwest Series with their seven-wicket victory at Lords. Here we look at how they can be expected to fare in the final three ODIs.
After losing the Ashes, can Michael Clarke and Australia salvage something from a disappointing tour of England with an ODI series victory?
At the beginning of the summer, Bettorlogic recommended England to lift the Ashes at a best price of 3.25.